Hi Priscilla. When you say it does not open, are you getting an error? A message? or nothing at all?
Does it happen with the 32-bit version or the 64-bit one or both? With PSP version? 2021 or a previous version? or all?
What is the W10 update that was just installed? I checked and mine shows 20H2. My PSP2021 opens fine (but I didn’t restart my system).
Anyone else can chime in to say if they have an issue or not with a W10 update?